Table 3.
Characteristics of the study participants among MC4R genotypes
| Variable | TT (n = 152) | TC + CC (n = 128) | P-value | P-value* |
|---|---|---|---|---|
| Demographic variables | ||||
| Age (years) | 37.23 ± 8.65 | 35.77 ± 8.03 | 0.14 | 0.15b |
| PA (MET-minutes/week) | 1238.64 ± 1892.47 | 1177.10 ± 2371.62 | 0.82 | 0.96b |
| Anthropometric parameters | ||||
| Weight (kg) | 81.06 ± 12.32 | 80.28 ± 12.48 | 0.60 | 0.44a |
| Height (m) | 161.90 ± 5.85 | 160.98 ± 5.81 | 0.19 | 0.03a |
| BMI (kg/m2) | 31.06 ± 4.66 | 30.78 ± 3.90 | 0.58 | 0.86b |
| WC (cm) | 99.16 ± 10.31 | 98.53 ± 9.81 | 0.60 | 0.63a |
| WHR | 0.93 ± 0.05 | 1.64 ± 8.04 | 0.27 | 0.95a |
| Body composition | ||||
| BFM (kg) | 34.02 ± 8.99 | 33.68 ± 8.30 | 0.74 | 0.64a |
| FFM (kg) | 47.27 ± 5.53 | 46.23 ± 5.57 | 0.11 | 0.09a |
| VFL | 16.42 ± 11.41 | 16.93 ± 17.32 | 0.76 | 0.44a |
| Blood pressure | ||||
| SBP (mmHg) | 112.16 ± 14.04 | 110.92 ± 13.78 | 0.46 | 0.49 |
| DBP (mmHg) | 77.92 ± 9.59 | 77.49 ± 9.87 | 0.71 | 0.71 |
| Blood parameters | ||||
| FBS (mmol/dl) | 87.94 ± 10.21 | 86.24 ± 8.46 | 0.16 | 0.63 |
| HOMA-IR | 3.36 ± 1.36 | 3.27 ± 1.17 | 0.61 | 0.46 |
| Total Cholesterol (mg/dl) | 185.19 ± 34.12 | 184.83 ± 38.08 | 0.93 | 0.63 |
| TG (g/dl) | 127.89 ± 74.23 | 114.52 ± 64.32 | 0.13 | 0.30 |
| HDL (mg/dl) | 46.35 ± 9.94 | 47.07 ± 11.98 | 0.60 | 0.46 |
| LDL (mg/dl) | 95.81 ± 23.23 | 93.84 ± 25.24 | 0.52 | 0.56 |
| LDL/HDL | 2.13 ± 0.58 | 2.06 ± 0.60 | 0.39 | 0.31 |
| CHOL/HDL | 4.17 ± 1.23 | 4.18 ± 1.83 | 0.95 | 0.78 |
| Inflammatory marker | ||||
| hs-CRP (mg/ L) | 4.15 ± 4.53 | 4.56 ± 4.77 | 0.50 | 0.69 |
Variables are presented as mean ± SD for continuous variables
P values from t test for continuous variables
PA physical activity, BMI Body mass index, WC waist circumference, WHR waist height ratio, BFM body fat mas, FFM fat free mass, VFL visceral fat level, SBP Systolic blood pressure, DBP Diastolic Blood Pressure, FBS Fasting blood sugar, HOMA-IR Homeostatic Model Assessment for Insulin Resistance, TG Triglyceride, LDL Low density lipoprotein, HDL, High density lipoprotein, hs-CRP High sensitivity C-reactive protein
*P-value was found by ANCOVA, and adjusted for age, BMI, physical activity, and total energy intake
aBMI considered as collinear, and adjusted for age, physical activity, and total energy intake
bRemoved the collinear variable from the GLM as confounders