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. 2022 Aug 29;63(9):31. doi: 10.1167/iovs.63.9.31

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Figure 3. — Genes of PCDHA cluster overlapping cg27494055 with decreased methylation level in HM children. The PCDHA gene cluster is tandemly localized on chromosome 5q31 and it consists of 15 genes and one pseudogene. The 13 upstream genes and the pseudogene have highly similar sequence, while a subfamily C contains two more (C1 and C2) distantly related coding sequences. The CG dinucleotide is localized in TSS1500 of PCDHA10 gene and in introns of PCDHA1–9. SNVs rs200661444 in exon 1 of PCDHA10, rs246073, and rs1581364290 colocalized with CG dinucleotide were indicated.