Table 1:
Demographics and Infection characteristics
N (%)† | |
---|---|
Total infections | 225 |
Total patients | 143 |
Total patients with ≥ 1 year follow-up | 142 (99.3) |
Survival at 30 days after first infection | 122 (85.9) |
Survival at 1 year after first infection | 94 (66.2) |
Survival at 1 year after transplant | 110 (77.5) |
Total pathogens | 237 |
Mean Age, years (STD) | 57.7 (11.7) |
Female (%) | 102 (45.3) |
Mean duration between transplant and infection, days (STD) | 193 (383.1) |
Organ received‡ (%) | |
Heart | 16 (7.1) |
Kidney | 69 (30.7) |
Liver | 68 (30.2) |
Lung | 7 (3.1) |
Multi-organ | 65 (28.9) |
Primary infection site (%) | |
Intra-abdominal | 21 (9.3) |
Biliary | 7 (3.1) |
Blood | 26 (11.6) |
Catheter | 2 (0.9) |
Respiratory | 55 (24.4) |
Urine | 100 (44.4) |
Other site | 14 (6.2) |
Multifocal infection | 53 (23.5) |
Infection at site of transplant (%) | 109 (48.4) |
Intra-abdominal§ | 18 (16.5) |
Biliary§ | 7 (6.4) |
Respiratory§ | 4 (3.7) |
Urine§ | 76 (69.7) |
Other§ | 3 (2.7) |
Carbapenem-resistant pathogen | 113 (50.2) |
Polymicrobial infection | 54 (24.0) |
Renal replacement therapy prior to infection | 52 (23.1) |
Infection requiring hospitalization | 207 (92.0) |
Infection requiring ICU admission | 130 (57.8) |
Pathogen (s) sensitive to empiric therapy | 94 (41.8) |
Final therapy different from empiric therapy | 152 (67.6) |
Multiple agents used for definitive therapy | 61 (27.1) |
Antibiotics completed as outpatient | 18 (8.0) |
Abbreviations: Intensive care unit (ICU)
Except when specified, (%) refers to percent of total infections (N=225)
Refers to most recent organ transplanted prior to infection for patients who underwent >1 transplant
Refers to percent of infections at site of transplant (N=109)