Table 2. α-Glucosidase Inhibitory Efficacy of the Synthesized Derivatives 1B–14Ba.
compound no. | glucosidase inhibitionIC50 ± SEMa (μM) | compound no. | glucosidase inhibitionIC50 ± SEMa (μM) |
---|---|---|---|
1B | 4.33 ± 0.41 | 8B | 9.44 ± 0.83 |
2B | 2.62 ± 0.30 | 9B | 8.56 ± 0.59 |
3B | 3.01 ± 0.29 | 10B | 9.01 ± 0.77 |
4B | 8.76 ± 0.62 | 11B | 10.11 ± 0.84 |
5B | 6.28 ± 0.71 | 12B | 3.79 ± 0.22 |
6B | 3.63 ± 0.36 | 13B | 3.28 ± 0.19 |
7B | 3.96 ± 0.42 | 14B | 3.34 ± 0.27 |
acarbose (standard) | 37.38 ± 1.37 |
IC50 values (mean ± standard error of the mean); Standard: Standard inhibitor for glucosidase.