Table 3. Effect of the Tested Synthetic Benzothiazepines on Blood Glucose in OGTT^a.

		blood glucose level in mg/dL
groups	dose (mg/kg)	0 min	30 min	60 min	90 min	120 min
control group (sugar-treated)		106.23 ± 4.91	177.26 ± 5.01!!!	154.82 ± 4.91!!!	135.21 ± 4.82!!!	128.87 ± 4.89!!!
2B	10	103.21 ± 4.13	118.61 ± 4.57*	113.31 ± 5.03*	111.90 ± 4.57*	109.20 ± 4.39
	20	101.38 ± 4.67	115.07 ± 4.61**	109.39 ± 4.56*	108.69 ± 4.11**	107.78 ± 4.75
3B	10	103.09 ± 4.03	119.71 ± 4.01*	119.98 ± 4.97*	115.92 ± 4.01*	111.82 ± 4.45
	20	101.33 ± 4.11	116.21 ± 4.45*	117.03 ± 4.71*	109.31 ± 4.21**	113.15 ± 4.13
6B	10	103.41 ± 4.05	125.39 ± 4.10*	120.41 ± 4.81*	112.61 ± 4.81*	114.91 ± 4.59
	20	100.93 ± 4.11	119.91 ± 4.62*	121.66 ± 4.31*	111.22 ± 4.21*	109.78 ± 5.01
7B	10	104.01 ± 4.97	120.71 ± 5.01*	120.90 ± 4.54*	116.52 ± 4.11*	109.25 ± 4.91
	20	103.88 ± 4.04	117.41 ± 4.70**	114.22 ± 4.97**	117.01 ± 4.66*	108.91 ± 4.87
12B	10	101.67 ± 4.55	121.63 ± 4.56*	122.02 ± 4.66*	115.31 ± 4.61*	114.19 ± 4.61
	20	105.59 ± 4.61	117.38 ± 4.01*	117.61 ± 4.60*	110.71 ± 4.91**	111.21 ± 4.31
13B	10	104.80 ± 4.97	120.04 ± 5.04*	118.31 ± 4.65*	109.81 ± 4.56**	113.93 ± 4.67
	20	103.79 ± 5.12	116.81 ± 4.31**	114.98 ± 4.34**	110.21 ± 3.91**	110.04 ± 4.81
14B	10	104.21 ± 4.67	124.02 ± 4.01*	119.33 ± 4.63*	114.98 ± 4.03*	116.49 ± 4.71
	20	103.87 ± 4.18	119.61 ± 4.55*	116.20 ± 4.78**	112.69 ± 4.11*	111.61 ± 4.97
std	0.5	102.03 ± 4.22	103.92 ± 5.01**	108.71 ± 4.21***	101.86 ± 4.21***	104.12 ± 4.67

^aAll values are expressed as means ± SEM, n = 8. One-way ANOVA and Dunnett’s post hoc multiple comparison test determines the values of P. ^!!!P < 0.001 as a comparison of the diabetic control group vs normal control, *P < 0.05, **P < 0.01, and ***P < 0.001 as a comparison of the diabetic control group vs test samples and glibenclamide-treated groups using one-way ANOVA followed by Dunnett’s comparison.