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. 2022 Aug 2;14(8):e27603. doi: 10.7759/cureus.27603

Figure 3. Pathology of the primary tumor.

Figure 3

A: Immunostaining for chromogranin AX200. Positive cytoplasmic staining indicating the neuroendocrine differentiation of neoplasmatic cells (NSCLC with endocrine features).

B: Hematoxylin-eosin (original magnification ×200). Part of the primary tumor revealing neuroendocrine-type cells with high nuclear-to-cytoplasm ratio, pleomorphism, and solid growth pattern (arrows), features of high-grade malignant neuroendocrine neoplasm (NSCLC).

NSCLC: non-small-cell lung cancer