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. 2022 Sep 1;14(1):128–136. doi: 10.1007/s13193-022-01636-1

Table 3.

A literature review of DFSP of the head and neck region

Author Year No. of patients Surgery Reconstruction method Recurrence Conclusion
Leon Barnes [6] 1984 17 Wide local excision (WLE) Primary/Grafting 53% Prognosis is related to the adequacy of excision, number of local recurrence, and histological appearances
Rufus J. Mark [7] 1993 16 WLE Primary/grafting 56% Wide surgical resection achieving good margins offers an excellent probability of cure
Timothy L. Parker [8] 1995 7 MMS Five patients had primary, one with cheek advancement, one with the secondary intension No recurrence at 3 years median follow-up Mohs surgery excises DFSP with maximum tissue conservation and a high cure rate
Chuan K Koh [9] 1995 8 WLE Primary excision and graft 12.5% Local recurrence is frequent. Wide surgical excision is the treatment of choice
Scott M. Gayner [10] 1997 32 WLE 34% (11 patients) Should use surgical margins of 2 cm
Alexander Stojadinovic [11] 2000 33 (21 primaries, 12 recurrences) WLE 9% (3 patients) Local recurrence-free survival depends on a negative histological margin. The frozen section analysis may not be accurate
William David Tom [12] 2003 Nine patients (2 recurrences, seven primaries) MMS 0 (median follow-up 43 months) Wide local excision with 2- to 3-cm margins results in an unacceptably high recurrence rate; larger excisional margins are necessary to remove all disease
Thiele OC [13] 2009 Seven patients (recurrent) WLE Five required grafts, two closed local advancement Two recurred, and salvage surgery for both Radical surgical removal is the treatment of choice
Able González [14] 2020 41 patients MMS MMS excision and grafts One patient (2.4%) MMS should be the standard treatment for DFSP