. Author manuscript; available in PMC: 2023 Jun 1.

Published in final edited form as: J Geriatr Oncol. 2022 Jan 5;13(5):624–628. doi: 10.1016/j.jgo.2021.12.010

Table 2:

Differences in Geriatric Assessment and Health-Related Quality of Life by Report of Polypharmacy

	Polypharmacy (≥9 medications)
	No	Yes	p-value
Geriatric Assessment Domains
≥1 falls, n (%)	38 (14.7)	32 (39.0)	<.0001
Impaired (≥2) ECOG performance status, n (%)	79 (29.6)	38 (45.2)	0.0080
Reported limitations in walking one block, n (%)	121 (45.7)	65 (76.5)	<.0001
Any IADL dependence, n (%)	115 (44.1)	61 (71.8)	<.0001
Any ADL dependence, n (%)	35 (13.2)	27 (32.5)	<.0001
Frail, n (%)	75 (27.8)	50 (57.5)	<.0001
Health-Related Quality of Life
Physical health score, mean (SD)	44.6 (10.8)	37.9 (9.4)	<.0001
Mental health score, mean (SD)	48.9 (9.7)	44.4 (9.0)	0.0001

Abbreviations: IADL, Instrumental Activities of Daily Living; ADL, Activities of Daily Living; SD, standard deviation.