Table 3:

Unadjusted and Adjusted Odds Ratios of Polypharmacy (≥9 medications per day) with Geriatric Assessment and Health-Related Quality of Life

Geriatric Assessment Domains	Unadjusted Odds, 95% CI	Adjusted Odds*, 95% CI
≥1 fall	3.71 (2.11-6.50)	3.34 (1.80-6.22)
Impaired (≥2) ECOG performance status	1.97 (1.19-3.25)	1.91 (1.09-3.32)
Reported limitations in walking one block	3.87 (2.22-6.75)	3.40 (1.82-6.33)
Any IADL dependence	3.23 (1.90-5.49)	2.86 (1.59-5.14)
Any ADL dependence	3.18 (1.78-5.69)	3.29 (1.72-6.29)
Frail	3.51 (2.13-5.80)	3.06 (1.73-5.41)
Health-Related Quality of Life
Physical health score, ≤40	2.82 (1.70-4.69)	2.82 (1.70-4.69)
Mental health score, ≤40	1.73 (1.03-2.91)	1.73 (1.03-2.91)

^*Adjusted for age, sex, race, cancer type, cancer stage, and comorbid medical conditions