Table 3. Radiographic and histopathologic features of retrospective cohort.
| Features | No antigen (N = 21) | 1 antigen (N = 88) | 2+ antigen (N = 27) | P value |
|---|---|---|---|---|
| HRCT pattern, N (%) | 0.13 | |||
| Definite UIP | 1 (4.8) | 2 (2.3) | 0 (0) | |
| Possible UIP | 0 (0.0) | 10 (11.4) | 0 (0) | |
| Inconsistent with UIP | 20 (95.2) | 76 (86.4) | 27 (100) | |
| Type of HP | 0.61 | |||
| Inflammatory | 2 (9.5) | 16 (18.2) | 4 (14.5) | |
| Fibrotic | 19 (90.5) | 72 (81.8) | 23 (85.2) | |
| HRCT honeycombing, N (%) | 5 (23.8) | 20 (22.7) | 8 (29.6) | 0.76 |
| Probability of HP based on HRCT, N (%)* | 0.39 | |||
| Indeterminate | 7 (33.3) | 23 (26.1) | 3 (11.1) | |
| Compatible | 2 (9.5) | 12 (13.6) | 5 (18.5) | |
| Typical | 12 (57.1) | 53 (60.2) | 20 (74.1) | |
| Inconsistent features | ||||
| Mid/upper lung predominant fibrosis | 7 (33.3) | 33 (37.5) | 6 (22.2) | 0.34 |
| Peribronchovascular predominance | 13 (61.9) | 36 (40.0) | 11 (40.7) | 0.20 |
| Extensive ground glass > reticulations | 11 (52.4) | 51 (58.0) | 16 (59.2) | 0.88 |
| Micronodules, No. (%) | 4 (19.0) | 19 (21.6) | 7 (25.9) | 0.84 |
| Mosaic attenuation in ≥ 3 lobes | 14 (66.7) | 62 (70.5) | 19 (70.4) | 0.94 |
| Cysts, No. (%) | 2 (9.5) | 10 (11.4) | 0 (0) | 0.19 |
| Consolidation, No. (%) | 1 (4.8) | 9 (10.2) | 0 (0) | 0.18 |