Older age |
SARS-CoV-2, SARS-CoV-1, MERS |
10.0, vs. 4.9% among those with an age greater than 65 years |
Elderly people have a higher risk of developing severe COVID-19 |
(Mehra et al. 2020; Petrilli et al. 2020; Williamson et al. 2020; Zhu 2019) |
Cardiovascular diseases |
SARS-CoV-2 |
10.2, vs. 5.2% among those without disease |
COVID-19 mortality is significantly high in patients with cardiovascular disease |
(Galbadage et al. 2020; Petrilli et al. 2020; Williamson et al. 2020; Zhu et al. 2020) |
Coronary artery diseases (CAD) |
SARS-CoV-2 |
15.3, vs. 5.6% among those without diseases |
Patients with CAD had more severe conditions than non-CAD patients, according to studies |
(Mehra et al. 2020) |
Current vs former smoking |
SARS-CoV-2 |
9.4, vs. 5.6% among former smokers or non-smokers |
COVID-19 infection is more common in smokers |
(Mehra et al. 2020; Williamson et al. 2020) |
Cardiac arrhythmia |
SARS-CoV-2 |
11.5, vs. 5.6% among those without arrhythmia |
In patients with COVID-19, there is an increased risk of cardiac arrhythmia |
(Mehra et al. 2020; Williamson et al. 2020) |
Type 2 diabetes (T2D) |
SARS-CoV-2 |
7.8 vs. 2.7% |
Diabetes patients are more likely to have a severe COVID-19 clinical course and a higher mortality rate |
(Williamson et al. 2020; Zhu et al. 2020) |
Obesity |
SARS-CoV-2 |
The case-fatality rate (CFR) was 2.3% among the 44,672, with obesity accounting for 7.3% (1,023) of the deaths with COVID-19 |
Through immunological, biochemical, and anatomical mechanisms, obesity is a highly risk factor for severe COVID-19 |
(Petrilli et al. 2020; Williamson et al. 2020; Yu et al. 2021b) |
Sex |
SARS-CoV-2, MERS |
Men 60% versus 40% women |
When compared to women, men have a higher risk factor for COVID-19 |
(Docherty et al. 2020; Galbadage et al. 2020; Williamson et al. 2020) |
Kidney diseases |
SARS-CoV-2, MERS |
16% (2830 deaths out of 17,506 cases confirmed) |
Chronic kidney disease was associated with higher mortality in hospitals |
(Bhatraju et al. 2020; Cheng et al. 2020; Docherty et al. 2020; Williamson et al. 2020) |
Hypertension |
SARS-CoV-2, MERS |
The CFR was 6.0 percent (1023 deaths out of 44,672 cases confirmed) |
Hypotension might face a greater risk of developing into a critical or mortal condition |
(Williamson et al. 2020; Wu and McGoogan 2020) |
Cancer |
SARS-CoV-2, MERS |
The CFR was 5.6% (1023 deaths out of 44,672 confirmed cases) |
Covid-19 causes severe problems in cancer patients |
(Wu and McGoogan 2020) (Moni and Liò 2014; Williamson et al. 2020) |