O' Dempsey 1996.

Methods	Women were randomized to receive either pneumococcal vaccine or control vaccine.
Participants	Country: The Gambia. Number: 75 women in the intervention group and 75 women in the control group. Mean age: 22.0 years. Mean gestational age: 38.0 weeks.
Interventions	23‐valent pneumococcal polysaccharide vaccine vs meningococcal vaccine.
Outcomes	Incidence of neonatal pneumonia. Incidence of neonatal meningitis. Incidence of neonatal otitis media. Neonatal antibody levels (GM). Maternal antibody levels (GM).
Notes
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Details were not reported.
Allocation concealment (selection bias)	Unclear risk	Details were not reported.
Blinding of participants and personnel (performance bias) All outcomes	Low risk	Lack of blinding would be unlikely to affect results.
Blinding of outcome assessment (detection bias) All outcomes	Low risk	Lack of blinding would be unlikely to affect results.
Incomplete outcome data (attrition bias) All outcomes	Low risk	1/150 were lost to follow‐up.
Selective reporting (reporting bias)	Low risk	All outcomes were predefined and reported.
Other bias	Unclear risk	Vaccines were provided by industry sponsorship, but none of the authors affiliated with the company.