Quiambao 2003.
Methods | The study was a randomized, controlled trial. | |
Participants | Country: Philippines.
Number: 106 women in the intervention group and 54 women in the control group. Mean age: 26.8 years. Mean gestational age: 27.3 weeks. |
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Interventions | 23‐valent pneumococcal polysaccharide vaccine. | |
Outcomes | Neonatal antibody levels (GM). | |
Notes | ||
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Details were not reported. |
Allocation concealment (selection bias) | Unclear risk | Details were not reported. |
Blinding of participants and personnel (performance bias) All outcomes | Low risk | Lack of blinding would be unlikely to affect results. |
Blinding of outcome assessment (detection bias) All outcomes | Low risk | Lack of blinding would be unlikely to affect results. |
Incomplete outcome data (attrition bias) All outcomes | High risk | Cord blood was obtained from 42/54 in the control group and 82/106 in the intervention group. |
Selective reporting (reporting bias) | Low risk | All outcomes were predefined and reported. |
Other bias | Low risk | The trial appears to be free of industry sponsorship. |