Fig. 5.

Combined effects adhere to age-dependent expansions. All 58-y 1-mm² paired parameter simulations from Fig. 3 are displayed where TP53 persistence ($\theta s$) is greater than NOTCH1 persistence ($f0$) (A) and $f0$ > $\theta s$ (B) (for $f0$ = $\theta s$ see SI Appendix). Individual clones are broken into three groups (passenger, NOTCH1, and TP53) with corresponding sizes of each clone.