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. 2022 Aug 24;119(35):e2121985119. doi: 10.1073/pnas.2121985119

Fig. 4.

Fig. 4.

PDE optimal control. (A) The optimal activity controls (ζ0(t),Δζ(t); Left) and corresponding trajectories for the state variables (X(t),R(t); Center) and the full drop profile (h(x, t); Right), obtained by numerical optimization for small surface tension or large active capillary number (γ=0.15, Caζ=383.66). The drop adopts a strongly asymmetric shape, with an advancing peak and receding tail, like in ref. 25. (B) Similar plots with the optimal activity controls (ζ0(t),Δζ(t); Left), and corresponding drop trajectory (X(t),R(t), Center; h(x, t), Right), now obtained for large surface tension or small active capillary number (γ = 2, Caζ=30.91). The transport plan fares poorly as the drops fails to reach the desired final position and size and wastes a significant amount of energy in futile size oscillations (R(t); Center) that don’t aid in transport. Both A and B are computed by using XT=0.8 and RT = 3 (X0=0 and R0=6 is kept fixed throughout), though similar policies are obtained for other values of XT/RT as well. (CE) The total cost (Copt; C), efficiency (ϵW [Eqs. 13 and 14]; D), and precision (X(T)/R(T); E) of the numerically computed optimal transport protocol plotted against Caζ, for different tasks labeled by increasing XT/RT (blue to green). Remarkably, the performance curves present an optimal trade-off in balancing active forces against passive ones to attain improved drop transport plans at intermediate values of Caζ.