Table 6.
Pearson's correlations (R2) between quantitative fovea parameters and qualitative macular changes in OCT morphotypes of the ERM with designation of the corresponding significance level (p-value). ∗p < 0,05, ∗∗p < 0,01, and ∗∗∗p < 0,001.
| OCT morphotypes | Qualitative macular changes | Quantitative fovea parameters | ||||
|---|---|---|---|---|---|---|
| CFT, µm | CONLT, µm | CINLT, µm | CIPLT, µm | MFT, µm | ||
| Groups 1–3, n = 159 | RPE lesions | 0,005, p=0,946 | −0,098, p=0,221 | −0,046, p=0,564 | −0,08, p=0,313 | −0,006, p=0,942 |
| Integrity of ellipsoid zone | 0,131, p=0,1 | 0,068, p=0,396 | −0,001, p=0,988 | −0,046, p=0,568 | 0,146, p=0,066 | |
| ELM integrity | 0,061, p=0,442 | −0,071, p=0,372 | 0,069, p=0,388 | −0,065, p=0,419 | 0,057, p=0,476 | |
| Distortion of the retinal layers | 0,292, p < 0, 001∗∗∗ | 0,248, p=0, 002∗∗ | 0,164, p=0, 039∗ | 0,113, p=0,154 | 0,287, p < 0, 001∗∗∗ | |
| Separation of ERM | 0,168, p=0, 034∗ | 0,094, p=0,24 | 0,106, p=0,184 | 0,066, p=0,406 | 0,187, p=0, 018∗ | |
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| Groups 4–5, n = 49 | RPE lesions | −0,163, p=0,262 | −0,238, p=0,1 | −0,015, p=0,919 | — | −0,284, p=0, 048∗ |
| Integrity of ellipsoid zone | 0,342, p=0, 016∗ | 0,293, p=0, 041∗ | 0,315, p=0, 027∗ | — | 0,165, p=0,258 | |
| ELM integrity | 0,548, p < 0, 001∗∗∗ | 0,514, p < 0, 001∗∗∗ | 0,579, p < 0, 001∗∗∗ | — | 0,285, p=0, 047∗ | |
| Distortion of the retinal layers | −0,024, p=0,868 | −0,007, p=0,962 | −0,151, p=0,3 | — | 0,384, p=0, 006∗∗ | |
| Separation of ERM | 0,151, p=0,3 | 0,169, p=0,244 | −0,035, p=0,811 | — | 0,397, p=0, 005∗∗ | |
ERM: epiretinal membrane, OCT: optical coherence tomography, RPE: retinal pigment epithelium, ELM: external retinal limiting membrane, ONL: outer retinal nuclear layer, IN: inner retinal nuclear layer, IPL: inner plexiform retinal layer, CFT: central foveolar retinal thickness, MFT: maximum foveal retinal thickness, CONLT: central foveolar ONL thickness, CINLT: central foveolar INL thickness, CIPLT: central foveolar IPL thickness, and n: number of patient eyes.