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. 2022 Aug 25;2022:1895498. doi: 10.1155/2022/1895498

Table 6.

Pearson's correlations (R2) between quantitative fovea parameters and qualitative macular changes in OCT morphotypes of the ERM with designation of the corresponding significance level (p-value). p < 0,05, ∗∗p < 0,01, and ∗∗∗p < 0,001.

OCT morphotypes Qualitative macular changes Quantitative fovea parameters
CFT, µm CONLT, µm CINLT, µm CIPLT, µm MFT, µm
Groups 1–3, n = 159 RPE lesions 0,005, p=0,946 −0,098, p=0,221 −0,046, p=0,564 −0,08, p=0,313 −0,006, p=0,942
Integrity of ellipsoid zone 0,131, p=0,1 0,068, p=0,396 −0,001, p=0,988 −0,046, p=0,568 0,146, p=0,066
ELM integrity 0,061, p=0,442 −0,071, p=0,372 0,069, p=0,388 −0,065, p=0,419 0,057, p=0,476
Distortion of the retinal layers 0,292, p < 0, 001∗∗∗ 0,248, p=0, 002∗∗ 0,164, p=0, 039 0,113, p=0,154 0,287, p < 0, 001∗∗∗
Separation of ERM 0,168, p=0, 034 0,094, p=0,24 0,106, p=0,184 0,066, p=0,406 0,187, p=0, 018

Groups 4–5, n = 49 RPE lesions −0,163, p=0,262 −0,238, p=0,1 −0,015, p=0,919 −0,284, p=0, 048
Integrity of ellipsoid zone 0,342, p=0, 016 0,293, p=0, 041 0,315, p=0, 027 0,165, p=0,258
ELM integrity 0,548, p < 0, 001∗∗∗ 0,514, p < 0, 001∗∗∗ 0,579, p < 0, 001∗∗∗ 0,285, p=0, 047
Distortion of the retinal layers −0,024, p=0,868 −0,007, p=0,962 −0,151, p=0,3 0,384, p=0, 006∗∗
Separation of ERM 0,151, p=0,3 0,169, p=0,244 −0,035, p=0,811 0,397, p=0, 005∗∗

ERM: epiretinal membrane, OCT: optical coherence tomography, RPE: retinal pigment epithelium, ELM: external retinal limiting membrane, ONL: outer retinal nuclear layer, IN: inner retinal nuclear layer, IPL: inner plexiform retinal layer, CFT: central foveolar retinal thickness, MFT: maximum foveal retinal thickness, CONLT: central foveolar ONL thickness, CINLT: central foveolar INL thickness, CIPLT: central foveolar IPL thickness, and n: number of patient eyes.