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. 2022 Aug 25;2022:9148257. doi: 10.1155/2022/9148257

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Copyright © 2022 Peng-Fei Ding et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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α-KG alleviated neuronal apoptosis induced by SAH. (a) CCK-8 detection of neurons in the control, SAH, and SAH+DMKG groups (one-way ANOVA, F = 17.74). (b, c) Expression of neuron cleaved caspase-3 in the control, SAH, and SAH+DMKG groups (one-way ANOVA, F = 28.54). (d, e) Neuronal apoptosis was detected by flow cytometry in the control, SAH, and SAH+DMKG groups (one-way ANOVA, F = 11.75). (f) Caspase-3 assay kit was used to detect the caspase-3 activity (one-way ANOVA, F = 45.36) (^∗P < 0.05, ^∗∗P < 0.01).