Example slides using hematoxylin and eosin staining in 140 Gy mice, A, and rats B. Features indicative of radionecrosis include reactive astrocytes C, black arrows, foamy macrophages C, red arrows, thrombosis(D, red arrows, neutrophils D, black arrows, microcavitation E, black arrows, vascular dilation, E, red arrows), microhemorrhage F, and gliosis F. Scale bars are 800 µm A, 1000 µm B, 20 µm C, and 50 µm D-F.