Table 2. HR for the incidence of erosive esophagitis by sitting time per day.
| Sitting time (hours/day) | Person-years | Incident cases | Incidence density (per 10 person-years) | Multivariable-adjusted HRa (95% CI) | |||
|---|---|---|---|---|---|---|---|
| Crude | Model 1 | Model 2 | Model 3 | ||||
| ≤ 6 | 5,097.7 | 533 | 1.046 | 1.00 | 1.00 | 1.00 | 1.00 |
| 7–8 | 4,004.5 | 396 | 0.989 | 0.96 (0.84–1.09) | 0.94 (0.82–1.07) | 0.94 (0.83–1.08) | 0.94 (0.82–1.08) |
| 9–10 | 5,988.4 | 592 | 0.989 | 0.93 (0.82–1.04) | 0.91 (0.80–1.02) | 0.90 (0.80–1.02) | 0.90 (0.80–1.02) |
| ≥ 11 | 5,406.5 | 527 | 0.975 | 0.90 (0.79–1.01) | 0.88 (0.76–0.99) | 0.87 (0.76–0.98) | 0.86 (0.76–0.98) |
| p for trend | 0.060 | 0.028 | 0.021 | 0.016 | |||
GERD: gastroesophageal reflux disease; HR: hazard ratio; CI: confidence interval.
aEstimated from Cox proportional hazards models. Multivariable model 1 was adjusted for age and sex; model 2: model 1 plus adjustment for alcohol intake, smoking status, educational level, history of diabetes, history of dyslipidemia; model 3: model 2 plus adjustment for exercise frequency.