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. 2022 Aug 25;37(9):2061–2067. doi: 10.1007/s00384-022-04243-2

Table 3.

Odds ratios (OR) (with 95% CI) of HER2 positive relative to HER2 negative by different characteristics of CRC patients

Crude Adjusted
OR (95% CI) P OR (95% CI) P
Sex

Male

Female

Ref.

0.729 (0.465, 1.141) 0.166

\
T stage

T1–T2

T3–T4

Ref.

1.072 (0.615, 1.868) 0.806

\
N stage

N0

N1–N2

Ref. 0.684 (0.437, 1.071) 0.097

Ref.

0.946 (0.553, 1.619) 0.839

Distant metastasis

Yes

No

Ref. 1.206 (0.617, 2.357) 0.584 \
TNM stage

I-II

III-IV

Ref. 0.700 (0.445, 1.100) 0.122 \
Vessel invasion

Yes

No

Ref. 0.534 (0.341, 0.835) 0.006

Ref.

0.550 (0.322, 0.941) 0.029

Perineural invasion

Yes

No

Ref. 0.735 (0.466, 1.158) 0.184 \
Tumor differentiation

High

Poor–moderate

Ref.

1.415 (0.442, 4.528) 0.559

\