Table 2.
Odds ratio (OR) and adjusted odds ratio (aOR) for variables associated with seropositivity
| Variable | Seropositivity n (%) | Unadjusted OR (96% CI) | p value | Adjusted OR (95% CI) | p value |
|---|---|---|---|---|---|
| No COVID working | 241/3913 (6.16) | 1 | - | 1 | - |
| COVID working | 169/1784 (9.47) | 1.59 (1.30 – 1.96) | <0.001 | 1.50 (1.22 – 1.84) | <0.001 |
| Female sex | 1 | - | 1 | - | |
| Male sex | 104/1293 (8.04) | 1.17 (0.93 – 1.47) | 0.18 | 1.10 (0.87 – 1.39) | 0.43 |
| Age | - | <0.001* | - | <0.001* | |
| Age 16-24 | 47/456 (10.3) | 1 | - | 1 | - |
| Age 25-34 | 152/1878 (8.1) | 0.77 (0.54 – 1.08) | 0.13 | 0.72 (0.51 – 1.02) | 0.069 |
| Age 35-44 | 102/1371 (7.4) | 0.70 (0.49 – 1.0) | 0.054 | 0.69 (0.48 – 0.99) | 0.044 |
| Age 45-54 | 71/1169 (6.1) | 0.56 (0.38 – 0.83) | 0.003 | 0.57 (0.38 – 0.83) | 0.004 |
| Age 55-64 | 32/721 (4.4) | 0.40 (0.25 – 0.64) | <0.001 | 0.44 (0.27 – 0.70) | 0.001 |
| Age 65-74 | 6/95 (6.3) | 0.59 (0.24 – 1.4) | 0.24 | 0.66 (0.27 – 1.59) | 0.34 |
| Age 75+ | 0/7 (0) | - | - | - | - |
| Job role | - | 0.0042* | - | 0.098* | |
| Administrative | 19/412 (4.61) | 1 | - | 1 | - |
| Nursing staff | 261 / 3471 (7.52) | 1.68 (1.04 – 2.71) | 0.033 | 1.52 (0.94 – 2.46) | 0.088 |
| Junior doctor | 10/118 (8.47) | 1.92 (0.87 – 4.24) | 0.11 | 1.43 (0.64 – 3.23) | 0.39 |
| Consultant | 10/174 (5.75) | 1.26 (0.57 – 2.77) | 0.56 | 1.19 (0.53 – 2.68) | 0.42 |
| Healthcare assistant | 36/319 (11.29) | 2.63 (1.48 – 4.68) | 0.001 | 2.06 (1.14 – 3.71) | 0.016 |
| Theatre staff | 3/24 (12.5) | 2.95 (0.81 – 10.78) | 0.10 | 2.40 (0.65 – 8.87) | 0.19 |
| Physiotherapist | 9/84 (10.71) | 2.48 (1.08 – 5.69) | 0.032 | 1.82 (0.78 – 4.24) | 0.16 |
| Domestic and porter | 4/27 (14.81) | 3.60 (1.13 – 11.44) | 0.030 | 3.45 (1.07 – 11.2) | 0.039 |
| Other | 58/1068 (5.43) | 1.19 (0.67 – 2.02) | 0.53 | 1.06 (0.62 – 1.80) | 0.85 |
| Ethnicity | - | - | <0.001* | - | <0.001* |
| White | 275/4467 (6.16) | 1 | - | 1 | - |
| Black | 22/120 (18.33) | 3.42 (2.12 – 5.52) | <0.001 | 3.42 (2.12 – 5.53) | <0.001 |
| Asian | 85/771 (11.02) | 1.89 (1.46 – 2.44) | <0.001 | 1.69 (1.30 – 2.19) | <0.001 |
| Chinese | 5/78 (6.41) | 1.04 (0.42 – 2.60) | 0.93 | 1.04 (0.42 – 2.60) | 0.94 |
| Mixed | 2/68 (2.94) | 0.46 (0.11 – 1.90) | 0.28 | 0.42 (0.10 – 1.71) | 0.23 |
| Other | 9/97 (9.28) | 1.56 (0.78 – 3.12) | 0.21 | 1.36 (0.68 – 2.74) | 0.38 |
| Not stated | 12/96 (12.5) | 2.18 (1.17 – 4.04) | 0.013 | 2.10 (1.13 – 3.90) | 0.019 |
aORs calculated using a multivariable model containing serostatus, age, sex, ethnicity, job role and COVID-working location.
*p value for the likelihood ratio test for the overall effect of variable