Table 1.
Number of patients: N (%) | IBCG (103) (%) | PBCG (417) (%) |
---|---|---|
BRCA1m | 65 (64.5) | 221 (53) |
BRCA2m | 38 (35.5) | 196 (47) |
BC Unilaterality | 92 (89.3) | 323 (77.4) |
Bilaterality | 11 (10.7) | 94 (22.6) |
Follow-up (median) | 65 months (5.4 years) | 111 months (9.3 years) |
Age at first breast cancer | Range: 24–81, median: 42 mean: 44.3 | Range: 21–80, median: 40 mean: 41.8 |
<30 | 6 (5.8) | 36 (8.6) |
(30–40) | 29 (28.2) | 165 (39.6) |
(40–50) | 40 (38.8) | 123 (29.5) |
(50–60) | 19 (18.5) | 65 (15.6) |
≥60 | 9 (8.7) | 28 (6.7) |
BMI | N = 102: median:22.6 Mean: 24 | N = 406: median: 22.5 mean: 23.5 |
Death during follow-up | 6 | 64 |
Breast cancer | 4 | 50 |
Ovarian cancer | 0 | 8 |
Pancreatic cancer | 1 | 1 |
Other cancer | 0 | 4* |
Other cause | 1 | 1 |
Number of prophylactic salpingo-oophorectomies | 83 | 298 |
Median age at surgery: | 45.4 (35–71) | 48.9 (31–73) |
Abbreviations: IBCG: incident breast cancer group, PBCG: prevalent breast cancer group.
*: 1 cholangiocarcinoma, 2 lung cancers, and 1 colorectal cancer.