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. 2022 Aug 19;13:934136. doi: 10.3389/fphar.2022.934136

TABLE 1.

NAFLD activity score (NAS).

WT WT dapa db/db db/db dapa
Steatosis 0 0 1.225 ± 0.160*** 0.175 ± 0.048### &
Lobular inflammation 0.125 ± 0.048 0.15 ± 0.065 0.400 ± 0.087* 0.100 ± 0.058#
Ballooning 0 0.050 ± 0.050 2 1.250 ± 0.218# &&
NAS 0.150 ± 0.050 0.200 ± 0.071 3.67 ± 0.236*** 1.525 ± 0.197### &&&

Values were mean ± SEM, n = 4. *p < 0.05, **p < 0.01, and ***p < 0.001 vs. wild-type mice (WT). # p < 0.05, ## p < 0.01, and ###p < 0.001 vs. db/db mice. & p < 0.05, && p < 0.01, and &&& p < 0.001 vs. dapagliflozin-treated wild-type mice. One-way ANOVA, Bonferroni’s multiple comparison test. Dapa = dapagliflozin.