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. 2022 Aug 19;13:948173. doi: 10.3389/fphar.2022.948173

TABLE 2.

Meta-analysis of arrhythmia patients’ treatment with Cordyceps.

Category n Participants, n (cases/controls) Heterogeneity SMD (95%CI) Z-test
Ph I2 (%)
Average heart rate
 Bradyarrhythmia 2 142/130 0.92 0 1.10 (0.85–1.36) z = 8.44; P z <0.00001
 Tachyarrhythmia 2 110/108 <0.00001 97 −1.14 (−2.83 to 0.56) z = 1.32; P z = 0.19
Minimal heart rate
 Bradyarrhythmia 2 142/130 <0.00001 97 0.99 (−0.49–2.46) z = 1.31; P z = 0.19
Inflammation index
 Hs-CRP 1 66/66 NA NA 2.86 (2.37–3.35) z = 11.46; P z <0.00001
 IL6 1 66/66 NA NA 2.29 (1.84–2.73) z = 10.15; P z <0.00001
 TNF 1 66/66 NA NA 2.13 (1.70–2.56) z = 9.72; P z <0.00001

P z <0.05 shows a significant association. CI, confidence interval; NA, not available; SMD, standardized mean difference; Ph, p-values.