TABLE 3.
Some selected SNPs and comparisons of their concepts under LitVar and SNPMap.
| SNPMap (Top keywords) | LitVar (Top keywords) | |
|---|---|---|
| rs10993994 | Diseases: Prostatic Neoplasms (93), Neoplasms (29), Mental Disorders (15), Breast Neoplasms (9), Colorectal Neoplasms (5) | Prostate cancer (228), Cancer (89), MSMB (43), PCA (35), Prostate-specific antigen (29), Tumor (28), PSA (25), KLK3 (16), Mortality (16), Androgen receptor, (15) etc |
| Chemicals: Igsf5 protein, rat (9), Androgens (6), Calcium (4), SS-B antigen (3), Carbon (3) | ||
| rs334 | Diseases: Sickle Cell Anemia (81), Systemic carnitine deficiency (48), Malaria (43), Anemia (40), Thalassemia (16), Genetic Diseases, Inborn (13) | Malaria (93), Sickle cell disease (91), HBB (53), Anemia (45), SCD (44), Thalassemia (36), Stroke (27), Mortality (26), Hydroxyurea (21), Infection, (21) etc |
| Chemicals: Glutamic Acid (13), Valine (10), Valine-Valine-Saquinavir (9), Oxytocin, Glu (4)- (8), Adenine (5) | ||
| rs7903146 | Diseases: Diabetes Mellitus (507), Type 2 Diabetes Mellitus (237), Obesity (130), Glucose Intolerance (40), Stroke (35) | Diabetes (692), TCF7L2 (556), Type 2 Diabetes (382), Glucose (303), Insulin (251), Transcription factor 7-like 2 (206), Obesity (154), Diabetic (134), Diabetes mellitus (127), Type 2 Diabetes Mellitus, (92) etc |
| Chemicals: Glucose (195), Cholesterol (41), Triglycerides (40), Metformin (27), Carbohydrates (22) | ||
| rs112445441 | Diseases: Colorectal Neoplasms (510), Neoplasms (451), Adenomatous Polyposis (59), Carcinoma, Non-Small-Cell (47), Melanoma (44) | KRAS (1198), Cancer (1084), Tumor (1030), Colorectal cancer (1018), EGFR (490), BRAF (466), CRC (386), NRAS (266), PIK3CA (240), Epidermal Growth Factor Receptor, (237) etc |
| Chemicals: AT 61 (53), Cetuximab (52), Guanosine Triphosphate (41), Glycine (32), irinotecan (25) | ||
| rs121913500 | Diseases: Glioma (774), Neoplasms (678), Glioblastoma (340), Astrocytoma (291), Oligodendroglioma (228) | Glioma (1328), Tumor (1307), Glioblastoma (890), Cancer (842), IDH1 (578), IDH (504), GBM (290), Brain tumor (246), Astrocytoma (242), IDH1/2, (184) etc |
| Chemicals: Alpha-hydroxyglutarate (144), Isocitrates (144), Arginine Vasopressin (72), Activated-Leukocyte Cell Adhesion Molecule (67), Histidine-pyridine-histidine-3 (55) |