Table 5.

Combined incidence of anxiety and depression and cervical cancer cohort to comparison cohort adjusted cohort hazard ratio by age, occupation, income, urbanization, and Charlson comorbidity index score.

Variable	CC control			Cervical cancer			HR (95% CI)
	Event, n	PY	Rate	Event, n	PY	Rate
Overall	3,714	203,189	18.3	3,634	167,182	21.7	1.17 (1.11-1.22)***
Age, years
18-39	300	27,120	11.1	401	21,653	18.5	1.63 (1.40-1.89)***
40-49	973	59,991	16.2	952	48,342	19.7	1.18 (1.08-1.29)**
50-64	1,385	70620	19.6	1,285	58,275	22.0	1.10 (1.02-1.19)*
65-74  75+	691 365	28,134 17,324	24.6 21.1	672 324	25,667 13,245	25.6 24.5	1.07 (0.96-1.19) 1.15 (0.99-1.34)
Occupation
Homemaker	1,206	65,362	18.5	1,152	52,531	21.9	1.16 (1.08-1.26)***
White collar	576	40,548	14.2	627	34,288	18.3	1.26 (1.12-1.40)***
Blue collar	1,496	73,822	20.3	1,393	62,784	22.2	1.08 (1.00-1.16)*
Other	436	23,458	18.6	462	17,579	26.3	1.37 (1.20-1.56)***
Income, NTD
≤20,000	2,318	117,010	19.8	2,233	95,869	23.3	1.15 (1.09-1.22)***
20,001-39,999	1,043	63868	16.3	1,011	52,493	19.3	1.16 (1.06-1.26)**
40,000+	353	22,311	15.8	390	18,820	20.7	1.27 (1.10-1.47)***
Urbanization
Urban	1,765	98,506	17.9	1,740	80,132	21.7	1.18 (1.11-1.26)***
Suburban	1,439	77,461	18.6	1,308	63,790	20.5	1.09 (1.01-1.17)*
Rural	510	27,223	18.7	586	23,260	25.2	1.32 (1.17-1.49)***
CCI score
0	3,379	187,765	18.0	3,282	152,701	21.5	1.17 (1.12-1.23)***
1+	335	15,424	21.7	352	14,481	24.3	1.12 (0.96-1.29)

PY, person-years; Rate, per 1,000 person-years; CCI, Charlson comorbidity index.

Adjusted for matched pair. *p < 0.05, **p < 0.01, ***p < 0.001.