Table 6.

Association between alcohol dependence and cannabis use once per week or more with employment status over 3-year follow-up (n = 1427)

Being unemployed over 3 years of follow-up
	Model 1a			Model 2b			Model 3c
	OR	95% CI		OR	95% CI		OR	95% CI
Substance use
Alcohol dependenced score < 3 and cannabis use less than once per week	Ref	–	–	Ref	–	–	Ref	–	–
Alcohol dependence score ≥ 3 or cannabis use once per week or more	1.47	1.09	1.98	1.48	1.10	2.01	1.43	1.05	1.93
Alcohol dependence score ≥ 3 and cannabis use once per week or more	2.74	1.56	4.80	2.75	1.60	4.72	2.44	1.44	4.12
Years of follow-up				0.76	0.66	0.86	0.76	0.67	0.87
Age				1.10	1.03	1.18	1.09	1.02	1.16
Gender
Men				Ref	–	–	Ref	–	–
Women				1.01	0.78	1.31	0.91	0.71	1.19
Education levele				0.60	0.49	0.74	0.63	0.51	0.78
Area deprivation indexf				1.01	0.93	1.08	1.01	0.93	1.08
Living place
With parents				Ref	–	–	Ref	–	–
Other				0.83	0.65	1.07	0.84	0.65	1.08
Depressive stateg
No							Ref	–	–
Yes							2.05	1.53	2.75

^aUnivariate analysis adjusted to years of follow-up

^bAdjusted for sociodemographic factors

^cAdjusted for sociodemographic factors and depressive state

^dAUDIT sub-score for alcohol dependence by adding the score of items 4, 5, 6, 7, 8, 9 and 10

^eBased on the International Standard Classification of Education

^fRepresenting spatial socioeconomic disparities

^gMeasured using the Center of Epidemiologic Studies Depression scale (CESD) and a score ≥ 19