Table 3.
Children's ASQ follow–up vs. non–follow–up.
| 1–HMRS with ASQ (n = 59), N (%) | 1–HMRS without ASQ (n = 10), N (%) | p–value | |
|---|---|---|---|
| Age of mother | 30.95 (6.2) | 28.75 (7.7) | 0.30 |
| Family SES | 48/60 (81) | 6/10 (60) | 0.61 |
| ACS | 48/60 (81) | 7/10 (70) | 0.6 |
| Weight <1,000 g | 26/59 (44) | 4/10 (40) | 1 |
| Male | 36/59 (61) | 6/10 (60) | 1 |
| GA weeks (mean +/–SD) | 28.1 (1.7) | 27.6 (1.3) | 0.38 |
| GA 240/7-276/7 weeks | 21/59 (36) | 6/10 (60) | 0.28 |
| GA 280/7-316/7 weeks | 38/59 (64) | 4/10 (40) | |
| Brain MRI abnormalities | |||
| WM injury score abnormal | 33/57 (57) | 6/10 (60) | 0.73 |
| GM injury score abnormal | 16/57 (28) | 0/10 (0) | 0.1 |
| DESHI | 37/57 (35) | 7/10 (30) | 1 |
| LVD | 23/54 (42) | 1/10 (10) | 0.23 |
| TCD | 16/54 (29) | 5/10 (50) | 0.30 |
| BPD | 23/54 (42) | 9/10 (90) | 0.018 |
| IHD | 37/54 (68) | 5/10 (50) | 0.64 |
| Metabolite peak area ratios (Time echo 135 ms) | |||
| NAA/Cho (in WM) | 0.68 (0.14) | 0.75 (0.10) | 0.068 |
| NAA/Cr (in WM) | 1.65 (0.75) | 1.29 (0.2) | 0.25 |
| CHO/Cr (in WM) | 2.41 (0.97) | 1.73 (0.16) | 0.015 |
| NAA/Cho (in GM) | 0.74 (0.16) | 0,73 (0.11) | 0.99 |
| NAA/Cr (in GM) | 1.28 (0.32) | 1.22 (0.13) | 0.73 |
| CHO/Cr (in GM) | 1.79 (0.52) | 1.7 (0.2.6) | 0.85 |
SES, socio–economic status; ACS, antenatal corticosteroid therapy; GA, gestational age; WM, white matter; GM, gray matter; DEHSI, diffuse excessive high signal intensity; TCD, Trans Cerebellum Diameter (moderate to severe anomaly, ≤47 mm); BPD, biparietal diameter (moderate to severe anomaly <72 mm); IHD, inter hemispheric diameter [Increased Extracerebral Space, moderate to severe abnormality (≥5 mm)], NAA, N Acetyl Aspartate; Cr, Creatinine; Cho, choline; Lac, lactate.