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. 2022 Aug 19;13:959978. doi: 10.3389/fphar.2022.959978

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Copyright © 2022 Zhang, Qin, Lyu, Lu, Chen, Fu and Yao.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Protein aggregation in control and lanosterol treated LBs in LB slices staining. (A,B) Similar with Figure 4, cells containing αA‐crystallin or αB‐crystallin protein aggregation (red arrows) were more abundant in control cloudy LBs on D45 compared with lanosterol treated LBs on D45, and ware nearly absent in all LBs on D25. (C,D) Quantification data showed that more cells containing protein aggregations were observed in control control LBs on D45 compared with control LBs on D25 and lanosterol treated LBs on D45. Bars represent mean ± SD. *p < .05, **p < .01, ***p < .001. Bar:50uM. DMSO, dimethyl sulfoxide. Lano, lanosterol.