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Performance of the prediction Nomo-score for estimating the risk of BRAF mutation.
| Value | Training cohort | Validation cohort |
|---|---|---|
| Cutoff value | 1.343 | 1.343 |
| Sensitivity | 75.6% | 55.6% |
| Specificity | 93.8% | 94.8% |
| Positive predictive value | 96.9% | 86.9% |
| Negative predictive value | 59.4% | 75.3% |
| Diagnostic accuracy | 80.6% | 78.1% |
| AUC (95% CI) | 0.685 (0.610 to 0.760) | 0.651 (0.532 to 0.770) |
AUC, area under the receiver operating characteristic curve; CI, confidence interval.
