Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Drugs for TNF-α mediated sphingomyelin signaling pathway from CHEMBL (https://www.ebi.ac.uk/chembl/).
| Drug Name | Chembl ID | Target | Mechanism | IC50 | References |
|---|---|---|---|---|---|
| Etanercept | Chembl1201572 | TNF-α | TNF-α inhibition | 10–12 | Tobinick (2016) |
| Nivocasan | Chembl2105721 | CASP 8, CASP 9 | CASP 8,9 inhibition | - | - |
| Scyphostatin | Chembl418376 | NSMase | Inhibitory activity against NSMase | 10–6 | Pitsinos et al. (2003) |
