Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Aug 19;9:907832. doi: 10.3389/fmolb.2022.907832

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2022 Zhang, Li, Cui, Wu, Jiao, Yu, Gu, Chen, Zhang and Yu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

OPLS-DA of the plasma metabolites between the noise group and control group. (A,B) OPLS-DA score plots between the noise group and control group in positive and negative ion modes, respectively. (C,D) Comparisons of the metabolites between the noise group and the control group in the positive and negative mode, respectively. (E,F) Top 50 differential metabolites with the smallest p values and VIP >1 between the noise group and the control group in the positive ion mode and negative ion mode, respectively. The Wilcoxon test and OPLS-DA were used for analyses, and they were performed in R 4.0.3 software. The metabolites with p < 0.05 in the Wilcoxon test and VIP >1 in the OPLS-DA were considered significant. OPLS-DA, orthogonal partial least squares discrimination analysis; VIP, variable importance in projection; log₂FC, log₂(fold change).