Table 4.
Estimated 1-Year Risks, Risk Differences, and Risk Ratios From an Observational Emulation of a Target Trial of Thrombus Aspiration Versus No Thrombus Aspiration, Stratified by Subpopulation, SWEDEHEART Registry, 2007–2016
| Thrombus Aspiration a | No Thrombus Aspiration a | RD a | 95% CI | RR | 95% CI a | |||
|---|---|---|---|---|---|---|---|---|
| Subpopulation and Outcome | Risk, % | 95% CI | Risk, % | 95% CI | ||||
| Sex | ||||||||
| Death | ||||||||
| Female | 13.2 | 10.8, 15.7 | 10.4 | 9.3, 11.6 | 2.8 | −0.1, 5.6 | 1.27 | 1.06, 1.51 |
| Male | 5.9 | 4.6, 7.2 | 6.1 | 5.5, 6.7 | −0.2 | −1.6, 1.2 | 0.96 | 0.81, 1.15 |
| Myocardial infarction | ||||||||
| Female | 4.4 | 2.3, 6.5 | 4.1 | 3.2, 4.9 | 0.3 | −2.0, 2.6 | 1.08 | 0.75, 1.57 |
| Male | 3.7 | 2.6, 4.8 | 4.1 | 3.5, 4.7 | −0.4 | −1.7, 0.9 | 0.91 | 0.72, 1.15 |
| Age | ||||||||
| Death | ||||||||
| ≥65 years | 12.0 | 10.1, 13.9 | 10.9 | 10.0, 11.8 | 1.1 | −0.9, 3.1 | 1.10 | 0.97, 1.25 |
| <65 years | 2.7 | 1.4, 3.9 | 2.7 | 2.2, 3.3 | −0.1 | −1.4, 1.3 | 0.98 | 0.68, 1.41 |
| Myocardial infarction | ||||||||
| ≥65 years | 4.2 | 2.8, 5.5 | 4.5 | 3.8, 5.1 | −0.3 | −1.8, 1.2 | 0.93 | 0.73, 1.19 |
| <65 years | 3.5 | 2.3, 4.8 | 3.5 | 2.9, 4.2 | 0.0 | −1.4, 1.4 | 1.00 | 0.76, 1.31 |
| Diabetes | ||||||||
| Death | ||||||||
| No | 7.5 | 6.2, 8.8 | 6.4 | 5.9, 7.0 | 1.0 | −0.4, 2.5 | 1.16 | 1.01, 1.34 |
| Yes | 9.9 | 6.2, 13.5 | 12.6 | 10.9, 14.4 | −2.8 | −6.5, 1.0 | 0.78 | 0.58, 1.05 |
| Myocardial infarction | ||||||||
| No | 3.8 | 2.8, 4.8 | 3.7 | 3.2, 4.2 | 0.1 | −1.0, 1.3 | 1.03 | 0.84, 1.27 |
| Yes | 3.9 | 1.1, 6.7 | 6.1 | 4.7, 7.4 | −2.2 | −5.3, 0.9 | 0.64 | 0.36, 1.12 |
| Previous Percutaneous Coronary Intervention | ||||||||
| Death | ||||||||
| No | 8.0 | 6.7, 9.3 | 7.4 | 6.8, 8.0 | 0.6 | −0.8, 2.0 | 1.08 | 0.95, 1.23 |
| Yes | 9.6 | 5.6, 13.5 | 6.7 | 5.0, 8.4 | 2.9 | −1.4, 7.2 | 1.43 | 0.98, 2.07 |
| Myocardial infarction | ||||||||
| No | 3.6 | 2.5, 4.6 | 3.6 | 3.2, 4.1 | −0.1 | −1.2, 1.1 | 0.98 | 0.78, 1.22 |
| Yes | 6.8 | 3.3, 10.3 | 7.7 | 5.8, 9.6 | −0.9 | −4.9, 3.2 | 0.89 | 0.58, 1.35 |
| Previous Myocardial Infarction | ||||||||
| Death | ||||||||
| No | 7.5 | 6.3, 8.7 | 6.8 | 6.2, 7.4 | 0.7 | −0.7, 2.1 | 1.10 | 0.96, 1.27 |
| Yes | 12.1 | 7.3, 16.8 | 11.0 | 9.3, 12.6 | 1.1 | −3.9, 6.1 | 1.10 | 0.80, 1.52 |
| Myocardial infarction | ||||||||
| No | 3.8 | 2.7, 4.9 | 3.5 | 3.1, 4.0 | 0.3 | −0.9, 1.4 | 1.08 | 0.87, 1.33 |
| Yes | 4.8 | 1.9, 7.7 | 7.6 | 6.0, 9.1 | −2.7 | −6.0, 0.6 | 0.64 | 0.40, 1.02 |
Abbreviations: CI, confidence interval; RD, risk difference, RR, risk ratio; SWEDEHEART, Swedish Web-Based System for Enhancement and Development of Evidence-Based Care in Heart Disease Evaluated According to Recommended Therapies.
a Adjusted at baseline for: age, sex, hospital, diabetes, body mass index, smoking, hyperlipidemia, hypertension, previous infarction, previous percutaneous coronary intervention, previous coronary artery bypass graft, stenosis class, proportion stenosis, angiography finding, heart rate, systolic blood pressure, diastolic blood pressure, thrombolysis, and use of warfarin, aspirin, clopidogrel, prasugrel, heparin, low molecular weight heparin, bivalirudin, or glycoprotein 2b/3a inhibitors.