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. Author manuscript; available in PMC: 2022 Sep 2.
Published in final edited form as: J Inherit Metab Dis. 2021 Feb 15;44(4):1013–1020. doi: 10.1002/jimd.12366

Figure 1.

Figure 1.

Correlation of UBDRS seizure assessment score to clinical, imaging and biochemical markers of CLN3 disease. Y-axis labels: A) Age (years), B) UBDRS Physical scores, C) UBDRS Capability assessment given actual vision scores, D-F) Tissue metabolite concentrations (difference from reference, mM), G) ABC standardized scores, H) CSF NEFL normalized protein expression by proximal extension assay, I) CSF NEFL concentrations (pg/mL) by ELISA. X-axis label: UBDRS seizure scores. ABC: Vineland-3 adaptive behavior composite. Corr: correlation coefficient. Cr: creatine. Glx: glutamate+glutamine+GABA. NAA: N-acetylaspartate. NEFL: neurofilament light chain. UBDRS: Unified Batten Disease Rating Scale.