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. 2022 Sep 2;2022(9):CD012337. doi: 10.1002/14651858.CD012337.pub2

16. Urgency urinary incontinence: cure or improvement, conservative versus conservative.

Analysis code (in review) Study ID Comparisons included Timing of measure Included trials (n) Effect measure Effect estimate (CI) Direction of effect Evidence of beneficial effect? Number of downgrades (reason for downgrade)
Moderate‐certainty evidence
4.2.1 Herderschee 2011 PFMT + BF vs PFMT + F IM Burgio 2002c1
(n = 110)
RR 1.0 (0.6 to 1.7) > 1 favours PFMT + feedback NO 2(E×2)
2.8.2 Stewart 2016 ES vs laseropuncture IM Kosilov 20132
(n = 114)
MD −1.8 (−2.3 to −1.3) < 0 favours ES YES favours ES 1(H)
4.2.1 Stewart 2016 ES + PFMT vs PFMT alone IM Schreiner 20102
(n = 51)
RR 0.56 (0.3 to 0.9) < 1 favours ES + other YES favours ES + PFMT 1(H)
4.3.1 Stewart 2016 ES + PFMT vs PFMT alone IM Schreiner 20102
(n = 51)
RR 0.3 (0.1 to 0.7) < 1 favours ES + other YES favours ES + PFMT 1(H)
2.3.1 Stewart 2016 ES vs PFMT IM Wang 20042
(n = 69)
RR 0.8 (0.5 to 1.2) < 1 favours ES NO 2(E×2)
2.3.2 Stewart 2016 ES vs PFMT +
biofeedback
IM Wang 20042
(n = 69)
RR 0.9 (0.6 to 1.6) < 1 favours ES NO 2(E×2)
2.8.1 Stewart 2016 ES vs PFMT IM Arruda 20082
(n = 42)
MD 0.1 (−8.7 to 8.9) < 0 favours ES NO 2(E×2)
Low‐certainty evidence
5.2 Rai 2012 Anticholinergic drugs + non‐drug therapies vs non‐drug therapies alone IM Park 2002
(n = 50)
RR 0.6 (0.3 to 1.3) < 1 favours anticholinergics + non‐drug therapies NO 4(E×2, H×2)
5.2 Rai 2012 Anticholinergic drugs + non‐drug therapies vs non‐drug therapies alone IM Song 2006
(n = 57)
RR 0.6 (0.3 to 1.2) < 1 favours anticholinergics + non‐drug therapies NO 3(E×2, H)
4.9.2 Stewart 2016 ES + PFMT vs PFMT IM Firra 20132
(n = 12)
MD 0.2 (−1.2 to 1.6) < 0 favours ES + other NO 3(A, E×2)

1Burgio 2002 was a three‐arm trial in which two of the groups received PFMT, combined with either feedback or biofeedback. Both groups received active treatment, each comprising a different way of delivering the same intervention.
2These trials compared ES with another conservative intervention. However, in all cases both conservative interventions were categorised as 'physical therapy' interventions.
Abbreviation: CI: confidence interval; ES: electrical stimulation; IM: immediate; MD: mean difference; n: number of participants assessed NOT to have been cured or improved using a variety of different assessment methods; RR: risk ratio.
Codes for GRADE assessment: A: blinding of outcome assessor; B: allocation concealment; C: differential attrition; D: ROBIS domain 2; E: CIs plus sample size; F: heterogeneity using I2 statistic; G: type of UI was unclear or not reported; H: unclear or not reported for blinding, allocation and differential attrition.