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. 2022 Sep 2;2022(9):CD012337. doi: 10.1002/14651858.CD012337.pub2

24. All types of urinary incontinence: primary outcome participant‐reported cure or improvement; conservative versus non‐conservative.

Analysis code (in review) Study ID Comparisons included Outcome measure (timing of measure) Included trials (n) Effect measure Effect estimate (CI) Direction of effect Evidence of beneficial effect? Number of downgrades (reason for downgrade)
Moderate‐certainty evidence
2.1.2 Alhasso 2005 Adrenergic agonist vs conservative therapy UC Wells 1991
(n = 157)
RR 1.4 (1.1 to 1.8) > 1 favours drug YES favours drugs 1(H)
Low‐certainty evidence
2.3.2 Alhasso 2005 Adrenergic agonist vs conservative therapy UC Wells 1991
(n = 86)
RR 0.9 (0.5 to 1.4) > 1 favours drug; differential dropout from groups, more from PFMT group (P < 0.01) NO 4(C, E×2, H)
1.3.1 Rai 2012 Anticholinergic drugs vs bladder training IM Macaulay 1987
(n = 29)
RR 1.0 (0.7 to 1.3) > 1 favours bladder training NO 3(E×2, H)

Abbreviations: CI: confidence interval; IM: immediate; n: number of participants; RR: risk ratio; UC: unclear.
Codes for GRADE assessment: A: blinding of outcome assessor; B: allocation concealment; C: differential attrition; D: ROBIS domain 2; E: CIs plus sample size; F: heterogeneity using I2 statistic; G: type of UI was unclear or not reported; H: unclear or not reported for blinding, allocation and differential attrition.