GRADE criteria	Risk of bias			Publication bias	Imprecision	Inconsistency	Indirectness
Item assessed for algorithm	Blinding of outcome assessor	Allocation concealment	Differential attrition	ROBIS domain 2	CIs + sample sizea	Heterogeneity, using I2 statisticb	Clinical heterogeneity
No downgrade	< 50% of participants are from trials with high risk of bias for this domain.	< 50% of participants are from trials with high risk of bias for this domain.	Chi2 testc, P ≥ 0.05 OR (if baseline participant numbers not available) < 50% participants are from trials with high risk of bias for differential attrition/loss to follow‐up.	Low or unclear risk of bias on ROBIS domain 2	If 95% CI excludes an RR of 1.0, or an MD of 0	I2 ≤ 50%	Data from participants with SUI and UUI is not combined. AND data from women who are antenatal and postnatal are not combined.
1 downgrade	≥ 50% of participants are from trials with high risk of bias for this domain.	≥ 50% of participants are from trials with high risk of bias for this domain.	YES differential attrition – Chi2 testc, P < 0.05 OR (if baseline participant numbers not available) ≥ 50% participants are from trials with high risk of bias for differential attrition/loss to follow‐up.	High risk of bias on ROBIS domain 2	If 95% CI includes an RR of 1.0, or an MD of 0 AND sample size < 344	I2 > 50%	If data from participants with SUI and participants with UUI are combined OR if data from women who are antenatal and postnatal (as defined by review authors) are combined OR both.
2 downgrades	—	—	—	—	If 95% CI includes an RR of 1.0, or an MD of 0 AND sample size < 258	I2 > 75%	—
CI: confidence interval; MD: mean difference; ROBIS: Risk of Bias In Systematic Reviews assessment tool; RR: risk ratio; SUI: stress urinary incontinence; UUI: urgency urinary incontinence.