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. 2022 Sep 1;21:168. doi: 10.1186/s12933-022-01606-5

Table 1.

Baseline characteristics according to tertiles of the TyG index

Total (n = 2792) T1 (n = 931) T2 (n = 941) T3 (n = 920) P-value
Age (years) 66 ± 10 68 ± 10 66 ± 10 63 ± 11  < 0.01
Male (n, %) 1927 (69.02%) 650 (69.82%) 643 (68.33%) 634 (68.91%)  < 0.01
SBP (mmHg) 136 ± 18 135 ± 18 136 ± 18 136 ± 19 0.11
DBP (mmHg) 77 ± 12 76 ± 12 77 ± 12 77 ± 12 0.03
FPG (mmol/l) 6.36 ± 2.22 5.29 ± 0.93 6.01 ± 1.40 7.81 ± 2.94  < 0.01
BMI (Kg/m2) 25.71 ± 3.34 24.74 ± 3.23 25.94 ± 3.11 26.45 ± 3.43  < 0.01
HDL-C (mg/dL) 1.04 ± 0.25 1.15 ± 0.27 1.03 ± 0.23 0.94 ± 0.21  < 0.01
LDL-C (mg/dL) 2.12 ± 0.80 1.89 ± 0.71 2.12 ± 0.74 2.36 ± 0.88  < 0.01
TC (mg/dL) 3.72 ± 0.93 3.45 ± 0.80 3.65 ± 0.84 4.07 ± 1.03  < 0.01
HbA1c (%) 6.59 ± 1.23 6.17 ± 0.87 6.45 ± 1.06 7.16 ± 1.45  < 0.01
eGFR (ml/min) 85.97 ± 17.08 86.24 ± 15.31 85.03 ± 16.33 86.65 ± 19.34 0.12
Smoking (n, %) 1299 (46.53%) 406 (43.61%) 432 (45.91%) 461 (50.11%) 0.02
Drinking (n, %) 1771 (63.43%) 584 (62.73%) 588 (62.49%) 599 (65.11%) 0.43
Hypertension (n, %) 1949 (69.81%) 595 (63.91%) 674 (71.63%) 680 (73.91%)  < 0.01
Glucose metabolism state
 NGR (n, %) 530 (18.98%) 275 (29.54%) 175 (18.60%) 80 (8.70%)  < 0.01
 Pre-DM (n, %) 1038 (37.17%) 394 (42.32%) 399 (42.40%) 245 (26.63%)  < 0.01
 DM (n, %) 1224 (43.84%) 262 (28.14%) 367 (39.00%) 595 (64.67%)  < 0.01
Medications
 Antiplatelets (n, %) 2643 (94.66%) 883 (94.84%) 883 (93.84%) 877 (95.33%) 0.34
 Antihypertensive drugs (n, %) 2317 (82.99%) 728 (78.20%) 795 (84.48%) 794 (86.30%)  < 0.01
 Antilipidemic drugs (n, %) 2629 (94.16%) 877 (94.20%) 878 (93.30%) 874 (95.0%) 0.30
 Multi-vessel CAD (n, %) 2159 (77.33%) 688 (73.90%) 736 (78.21%) 735 (79.89%)  < 0.01

TyG triglyceride–glucose, SBP systolic blood pressure, DBP diastolic blood pressure, FPG fasting plasma glucose, BMI body mass index, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, TC total cholesterol, HbA1c glycated hemoglobin A1c, eGFR estimated glomerular filtration rate, NGR normoglycemia, Pre-DM pre-diabetes mellitus, DM diabetes mellitus, CAD coronary artery disease