Table 4.
Associations between the TyG index and severity of CAD according to different diabetes statuses
| Glucose metabolism state | Model 1 | Model 2 | Model 3 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| OR | 95% CI | P-value | OR | 95% CI | P-value | OR | 95% CI | P-value | |
| NGR | |||||||||
| TyG index | 0.825 | 0.559–1.216 | 0.331 | 0.929 | 0.617–1.398 | 0.723 | 0.846 | 0.551–1.299 | 0.444 |
| T1 | Reference | Reference | Reference | ||||||
| T2 | 1.206 | 0.787–1.848 | 0.389 | 1.246 | 0.759–2.045 | 0.385 | 1.167 | 0.710–1.916 | 0.543 |
| T3 | 0.660 | 0.393–1.109 | 0.117 | 0.739 | 0.400–1.366 | 0.335 | 0.684 | 0.371–1.262 | 0.225 |
| Pre-DM | |||||||||
| TyG index | 1.210 | 0.910–1.607 | 0.189 | 1.412 | 1.043–1.903 | 0.023 | 1.367 | 1.000–1.867 | 0.049 |
| T1 | Reference | Reference | Reference | ||||||
| T2 | 1.161 | 0.844–1.597 | 0.359 | 1.230 | 0.859–1.761 | 0.258 | 1.217 | 0.860–1.724 | 0.268 |
| T3 | 1.351 | 0.927–1.968 | 0.118 | 1.613 | 1.050–2.477 | 0.029 | 1.541 | 1.013–2.344 | 0.043 |
| DM | |||||||||
| TyG index | 1.162 | 0.931–1.449 | 0.185 | 1.230 | 0.982–1.542 | 0.072 | 1.214 | 0.963–1.530 | 0.100 |
| T1 | Reference | Reference | Reference | ||||||
| T2 | 1.282 | 0.857–1.918 | 0.226 | 1.341 | 0.871–2.064 | 0.182 | 1.265 | 0.849–1.884 | 0.249 |
| T3 | 1.300 | 0.901–1.875 | 0.161 | 1.390 | 0.934–2.069 | 0.104 | 1.321 | 0.921–1.914 | 0.141 |
Model 1: unadjusted
Model 2: adjusted for age and sex
Model 3: adjusted for sex, age, BMI, smoking, drinking, hypertension, eGFR, antiplatelet drug use, antilipidemic drug use, and antihypertensive drug use
TyG triglyceride–glucose, CAD coronary artery disease, OR odds ratio, CI confidence interval, BMI body mass index, eGFR estimated glomerular filtration rate, NGR normoglycemia, Pre-DM pre-diabetes mellitus, DM diabetes mellitus