Table 3.
Intra-individual differences between cancellous and cortical compartments within patients with T2DM and within healthy individuals.
| Patients with diabetes | Healthy individuals from reference cohorts | |||
|---|---|---|---|---|
| Mean intra-individual difference Δ (Cn – Ct) | Significance (by pairwise comparison) | Mean intra-individual difference Δ (Cn – Ct) | Significance (by pairwise comparison) | |
| CaMean (wt%) | 0.44 | <0.001 | 0.30 | <0.001 |
| CaPeak (wt%) | 0.46 | <0.001 | 0.25 | 0.002 |
| CaWidth (Δwt%) | -0.20 | 0.002 | -0.23 | 0.012 |
| CaLow (%B.Ar) | -0.79 | <0.001 | -0.64 | 0.049 |
| CaHigh (%B.Ar) | 2.09 | <0.001 | 0.87 | 0.010 |
| CaYoung (wt%) | 0.76 | <0.001 | n.a.1 | n.a. |
| OLS-porosity (%) | -0.04 | 0.012 | 0.04 | n.s. |
| OLS-density (nb/mm2) | -30.7 | 0.002 | -3.6 | n.s. |
| OLS-area (µm2) | 1.04 | n.s. | 2.14 | n.s. |
| OLS-perimeter (µm) | 1.04 | 0.02 | 1.28 | n.s. |
| OLS-aspect ratio | 0.30 | <0.001 | 0.26 | n.s. |
Mean intra-individual difference is the mean of the absolute differences from each individual of the study group.
Significance represents the p-value based on paired t-tests or Wilcoxon signed rank tests.
1 n.a.=not available as iliac crest bone samples from reference cohort[22] are autopsy samples which are not tetracycline labeled.