TABLE 1.

Other promising natural products for treating SARS-CoV-2 infection in vitro.

No.	Name	Structure	EC50 or IC50 (μM)	Strain	Refs
1	Aloin A		15.68	Vero E6 cells	Lewis et al. (2022)
2	Aloin B		17.51	Vero E6 cells	Lewis et al. (2022)
3	Andrographolide		0.034	Calu-3 cells	Sa-Ngiamsuntorn et al. (2021), Schulte et al. (2022)
4	Aspulvinone D		10.3	J774A.1 cells	Liang et al. (2022)
5	Aspulvinone M		9.4	J774A.1 cells	Liang et al. (2022)
6	Aspulvinone R		7.7	J774A.1 cells	Liang et al. (2022)
7	(+)-Aureol		4.00	Calu-3 cells	Chhetri et al. (2022)
8	Baicalein		1.11	E. coli BL21 cells	Wu et al., 2022a, Xiao et al. (2021)
9	Baicalin		8.8	Vero E6 cells	Ngwe Tun et al. (2022)
10	Bromophycolide A		6.90	Calu-3 cells	Chhetri et al. (2022)
11	Bufotalin		0.072	Vero E6 cells	Jin et al. (2021)
12	Cannabidiol		1.24	A549-ACE2 cells	Corpetti et al. (2021), Nguyen et al. (2022)
13	Cannabidiolic acid		24 μg/mL	Vero E6 cells	van Breemen et al. (2022)
14	Cannabigerolic acid		37 μg/mL	Vero E6 cells	van Breemen et al. (2022)
15	Chebulagic acid		9.76	Vero E6 cells	Du et al. (2021)
16	Cinobufagin		0.072	Vero E6 cells	Corpetti et al. (2021), Nguyen et al. (2022)
17	Cinobufotalin		0.399	Vero E6 cells	Jin et al. (2021)
18	Corilagin		24.9	HEK293 cells	Yang et al. (2021a)
19	Curcumin		11.9	Vero E6 cells	Bahun et al. (2022)
20	Cyclopeniol		0.39	RAW264.7 cells	Thissera et al. (2021)
21	Cyclopeptin		0.40	RAW264.7 cells	Thissera et al. (2021)
22	Dehydrocyclopeptin		0.89	RAW264.7 cells	Thissera et al. (2021)
23	Dieckol		4.50	Vero E6 cells	Yan et al. (2021)
24	Digitoxin		0.059	Vero E6 cells	Caohuy et al. (2021), Jin et al. (2021), Caohuy et al. (2022)
25	Dihydromyricetin		1.14	Vero E6 cells	Su et al. (2021), Xiao et al. (2021)
26	Dihydrotanshinone I		8.14	Vero E6 cells	Ma and Wang, (2022)
27	Dithymoquinone		0.275 μg/mL	Vero E6 cells	Esharkawy et al. (2022)
28	Echinulin		3.90	Vero E6 cells	Alhadrami et al. (2022)
29	EGCG		4.24	Vero E6 cells	Chiou et al. (2022)
30	Ellagic acid		11.8	Vero E6 cells	Bahun et al. (2022)
31	(-)-Gallocatechin gallate		5.77	Vero E6 Cells	Xiao et al. (2021)
32	Glabridin		2.5	Vero E6 cells	Ngwe Tun et al. (2022)
33	Hesperidin		51.5	Vero E6 cells	Huang et al. (2022)
34	Isopetasin		0.37	Vero E6 cells	Urda et al. (2022)
35	Ivermectin		0.55	Vero E6 cells	Chable-Bessia et al. (2022)
36	Licoflavone C		1.34	Vero E6 cells	Corona et al. (2022)
37	LPC (14:0/0:0)		0.92	Vero E6 cells	Du et al. (2022)
38	LPC (16:0/0:0)		1.48	Vero E6 cells	Du et al. (2022)
39	LPC (16:0/18:1)		0.14	Vero E6 cells	Du et al. (2022)
40	Myricetin		0.63	Vero E6 cells	Kato et al. (2021), Su et al. (2021)
41	Neferine		0.36	HEK293/hACE2 cells	Yang et al. (2021b)
42	(+)-Neoechinulin A		0.47	Vero E6 cells	Alhadrami et al. (2022)
43	Neoechinulin B		32.9	Vero E6 cells	Nishiuchi et al. (2022)
44	Neopetasin		1.26	Vero E6 cells	Urda et al. (2022)
45	Oridonin		2.16	Vero E6 cells	Zhong et al. (2022)
46	Petasin		10.79	Vero E6 cells	Urda et al. (2022)
47	PGG		3.66	Vero E6 cells	Chiou et al. (2022)
48	Piniterpenoid A		64.5	Vero E6 cells	Li et al. (2021b)
49	Piniterpenoid C		76.1	Vero E6 cells	Li et al. (2021b)
50	Plitidepsin		0.0043	Vero E6 cells	Guisado-Vasco et al. (2022), Sachse et al. (2022)
51	Punicalagin		6.19	Vero E6 cells	Saadh et al. (2021) Suručić et al. (2021)
52	Resibufogenin		1.606	Vero E6 cells	Jin et al. (2021)
53	Salvianolic acid A		2.49	Vero E6 cells	Zhong et al. (2022)
54	Sangivamycin		0.015	Vero E6 cells	Bennett et al. (2022)
55	Scutellarein		5.68	E. coli BL21 cells	Wu et al. (2022c)
56	(+)-Shikonin		4.38	Vero E6 cells	Zhao et al. (2021), Ma et al. (2022)
57	Shikonin		4.50	Vero E6 cells	Cui and Jia (2021), Zhao et al. (2021)
58	Sulforaphane		2.40	Caco-2 cells	Ordonez et al. (2022)
59	Tanshinone IIA		7.82 μg/mL	Vero E6 cells	Elebeedy et al. (2022)
60	Telocinobufagin		0.142	Vero E6 cells	Jin et al. (2021)
61	Thymohydroquinone		0.023 μg/mL	Vero E6 cells	Esharkawy et al. (2022)
62	Tubercidin		0.05	Calu-3 cells	Schultz et al. (2022)
63	Ugonin J		2.38	Vero E6 Cells	Chiou et al. (2021)
64	5,3′,4′-trihydroxyflavone		8.22	Vero E6 cells	Zhao et al. (2021)
65	7-OH-Cannabidiol		3.60	A549-ACE2 cells	Nguyen et al. (2022)