Table 2.
Spectroscopy variable | Control (n = 16) | Patients (n = 34) | |||
---|---|---|---|---|---|
Pre-chemotherapy | Mid-chemotherapy | End-chemotherapy | One year | ||
Pi:PCr resting | 0.10 (0.02) | 0.11 (0.02) | 0.12 (0.03)a | 0.12 (0.02)a | 0.12 (0.02)a |
Pi:PCr 40% intensity | 0.31 (0.08) | 0.29 (0.07) | 0.34 (0.08)a | 0.32 (0.07)a | 0.32 (0.06)ab |
Pi:PCr 80% intensity | 0.61 (0.17) | 0.58 (0.22) | 0.62 (0.19)a | 0.56 (0.17) | 0.56 (0.22)b |
Pi:PCr peak exercise | 0.84 (0.23) | 0.78 (0.29) | 0.84 (0.26) | 0.74 (0.22)‡ | 0.72 (0.28) |
pH resting | 7.09 (0.11) | 7.07 (0.05) | 7.09 (0.07) | 7.07 (0.04) | 7.08 (0.04) |
pH 40% intensity | 7.07 (0.08) | 7.08 (0.06) | 7.06 (0.07) | 7.09 (0.04) | 7.11 (0.06) |
pH 80% intensity | 6.75 (0.3) | 6.86 (0.19) | 6.79 (0.22)a | 6.84 (0.20) | 6.90 (0.21)b |
pH peak exercise | 6.62 (0.28) | 6.73 (0.21) | 6.67 (0.22) | 6.73 (0.29) | 6.77 (0.24) |
PCr recovery time constant (s) | 33 (9) | 37 (13) | 40 (17) | 38 (11) | 33 (10)b |
Different from pre-chemotherapy (P ≤ .05).
Different from mid-chemotherapy (P ≤ .05).