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. 2022 Aug 24;7(1):122–144. doi: 10.20411/pai.v7i1.525

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Figure 2. — Intranasal 5-A-RU has no effect on protein or polysaccharide-specific antibody responses when administered with a live V. cholerae vaccination. (A-D) Serum day 35 endpoint (left) and time-course (right) (A) CT-IgG, (B) CT-IgA, (C) OSP-IgG, and (D) OSP-IgA ELISAs. (E-H) BAL fluid day 35 endpoint (E) CT-IgG, (F) CT-IgA, (G) OSP-IgG, and (H) OSP-IgA ELISAs. Data are represented as ELISA units measured kinetically and normalized to positive control pooled serum from WT B6 mice intranasally vaccinated with live V. cholerae. Data are represented as Median with IQR from 3 independent experiments. n=11-12 mice per group. *P < 0.05, **P > 0.01, ***P > 0.001, ***P > 0.0001 by 2-tailed Mann-Whitney U test.