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. 2022 Aug 24;7(1):122–144. doi: 10.20411/pai.v7i1.525

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Figure 3. — Intranasal 5-A-RU has no effect on protein or polysaccharide-specific antibody-secreting cell frequency in live V. cholerae vaccination. (A) Representative CT-IgG (left) and CT-IgA (right) ELISpot images from day 35 endpoint lung (top) and spleen (bottom) cells. (B-E) lung and spleen CT-IgG (B-C) and CT-IgA (D-E) ASC frequency per 10⁶ live cells. Data are represented as Median with IQR from 1 independent experiment. n=5 mice per group. (F) Representative OSP-IgG (left) and OSP-IgA (right) ELISpot images from day 35 endpoint lung (top) and spleen (bottom) cells. (G-J) lung and spleen OSP-IgG (G-H) and OSP-IgA (I-J) ASC frequency per 10⁶ live cells. Data are represented as Median with IQR from 2 independent experiments. n=10 mice per group. P values determined by 2-tailed Mann-Whitney U test.