Table 3. Cox proportional hazards analysis for overall survival.

Variable (univariate analysis)	Hazard	Referent	HR (95% CI)	P-value
Age	≥65 years	<65 years	1.49 (0.60–3.67)	0.39
Sex	Male	Female	1.22 (0.52–2.87)	0.65
Location	Trunk	Extremities	1.99 (0.86–4.63)	0.11
Size	≥5 cm	<5 cm	3.45 (1.27–9.37)	0.015
Distant metastases upon initial diagnosis	Positive	Negative	3.50 (1.43–8.56)	0.006
Grade	High	Low	2.16 (0.72–6.49)	0.17
Skin invasion	Positive	Negative	4.59 (1.89–11.2)	<0.001
Variable (multivariate analysis)	Hazard	Referent	HR (95% CI)	P-value
Distant metastases upon initial diagnosis	Positive	Negative	2.50 (0.97–6.39)	0.0567
Skin invasion	Positive	Negative	3.55 (1.39–9.03)	0.008

HR, hazard ratio; CI, confidence interval; P-value, P-value from Cox regression analysis