Table 1. Demographics and clinical characteristics.
| Healthy controls | Melancholia | Group comparison,t or χ2, p-value | |
|---|---|---|---|
| Number of participants | 38 | 30 | – |
| Age, mean (SD) | 46.5 (20.0) | 46.2 (15.5) | 0.95 |
| Sex (M:F) | 13:19 | 17:13 | 0.21 |
| Medication, % yes (n) | |||
| Any psychiatric medication | 7% (1) | 85% (23) | – |
| Nil medication | 93% (13) | 15% (4) | – |
| Selective serotonin reuptake inhibitor | 7% (1) | 15% (4) | – |
| Dual-action antidepressant* | 0% (0) | 48% (13) | – |
| Tricyclic or monoamine oxidase inhibitor | 0% (0) | 19% (5) | – |
| Mood stabiliser† | 0% (0) | 11% (3) | – |
| Antipsychotic | 0% (0) | 33% (9) | – |
*
For example, serotonin noradrenaline reuptake inhibitor.
†
For example, lithium or valproate.