rCBF dynamic before arousal in low and high NDS groups and ROC curves for representative rCBF. A, Comparisons of rCBF between low and high NDS groups from (−96)- to 0-min before spontaneous arousal in CA animals (n=5 per group). B, ROC curves for rCBF, including cortex, thalamus, and cerebellum, in the prediction of neurological outcome. Data represents as mean ± SEM. Comparisons between low and high NDS groups in rCBF performed with 2-way ANOVA with Bonferroni correction; ROC curve with concordance probability method used to determine optimal cutoff values of rCBF in cortex, thalamus and cerebellum. * p<0.05, ** p<0.01, *** p<0.001, **** p<0.0001. CA, cardiac arrest; CBF, cerebral blood flow; NDS, neurologic deficit scale; rCBF, regional cerebral blood flow.