. 2022 Sep 2;101(35):e30144. doi: 10.1097/MD.0000000000030144

Table 1.

Time-weighted sum of pain intensity differences and area under the curve of 180 and 360 min for NRS (rest, movement, and pressure).

Parameter	Group	NRS rest			NRS movement			NRS pressure
Parameter	Group	Mean ± SD	Mean difference (95% CIs)	P 2-sided^*	Mean ± SD	Mean difference (95% CIs)	P 2-sided^*	Mean ± SD	Mean difference (95% CIs)	P 2-sided^*
SPID (0–180)	Placebo	−15.3 ± 100.28	−657.7 (−714.83 to −600.52)	<.001	17.2 ± 127.33	−688.5 (−749.83 to −627.25)	<.001	23.8 ± 115.14	−664.78 (−725.32 to −604.25)	<.001
SPID (0–180)	TBF	642.4 ± 294.79	−657.7 (−714.83 to −600.52)	<.001	705.8 ± 308.93	−688.5 (−749.83 to −627.25)	<.001	688.5 ± 309.17	−664.78 (−725.32 to −604.25)	<.001
AUC (0–180)	Placebo	−13.7 ± 87.68	−564.4 (−617.1 to −511.78)	<.001	15.7 ± 113.17	−590.2 (−646.19 to −534.25)	<.001	21.6 ± 102.49	−567.99 (−623.68 to −512.3)	<.001
AUC (0–180)	TBF	550.7 ± 273.1	−564.4 (−617.1 to −511.78)	<.001	606.0 ± 283.35	−590.2 (−646.19 to −534.25)	<.001	589.6 ± 285.61	−567.99 (−623.68 to −512.3)	<.001
SPID (0–360)	Placebo	−34.7 ± 282.97	−1978.5 (−2073.99 to −1882.9)	<.001	36.4 ± 323.28	−2043.5 (−2150.92 to −1935.99)	<.001	50.1 ± 292.14	−2022.08 (−2122.86 to −1921.29)	<.001
SPID (0–360)	TBF	1943.8 ± 438.43	−1978.5 (−2073.99 to −1882.9)	<.001	2079.8 ± 489.9	−2043.5 (−2150.92 to −1935.99)	<.001	2072.2 ± 466.42	−2022.08 (−2122.86 to −1921.29)	<.001
AUC (0–360)	Placebo	−33 ± 266.65	−1860.13 (−1953.06 to −1767.2)	<.001	34.7 ± 305.58	−1920.95 (−2025.46 to −1816.45)	<.001	47.7 ± 276.37	−1900.18 (−1998.43 to −1801.92)	<.001
	TBF	1827.2 ± 431.74	−1860.13 (−1953.06 to −1767.2)		1955.7 ± 481.99	−1920.95 (−2025.46 to −1816.45)		1947.9 ± 459.79	−1900.18 (−1998.43 to −1801.92)

AUC = area under the curve; NRS = numerical pain rating scale; SPID = sum of pain intensity difference; TBF = turmeric-boswellia formulation.

Mann–Witney test.