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. 2022 Aug 19;14:934406. doi: 10.3389/fnagi.2022.934406

Figure 2.

Figure 2

The role of irisin in aging resistance. Aging reduces baseline levels of irisin in vivo. Irisin inhibits JNK phosphorylation and affects telomerase activity and expression of inflammatory factors. Induces autophagy and apoptosis resistance and decreases markers of senescence.