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. 2022 Jan 31;7(2):312–326. doi: 10.1038/s41564-021-01049-w

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© The Author(s) 2022, corrected publication 2022

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Extended Data Fig. 5 — Comparison of granulocyte (a) and monocyte (b) haQTL effect size between the Singapore discovery cohort (Chinese) and the European cohort¹⁹. Each dot represents an haQTL in the Singapore discovery cohort (x-axis) and a corresponding European¹⁹ haQTL in LD with the former. Effect size is defined as the regression coefficient beta relating ChIP-seq peak height to genotype. R: Pearson correlation. P-value: two-sided Pearson correlation P-value. (c) Cumulative minor allele frequency distributions for granulocyte and monocyte haQTLs in the Singapore discovery cohort (Chinese) and the European dataset¹⁹. Blue curves: shared haQTLs. Red curves: cohort-specific haQTLs. The statistical significance (Kolmogorov-Smirnov test, two-sample, two-sided) of the shift in allele frequency between shared and non-shared haQTLs is indicated in each panel.

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